Home

Sitemap

Accessibility

References

Reference sections:

GORD
LPR / EOR
Barrett's oesophagus
Hiatus hernia
Pregnancy
Children
Economics
Treatment options
Alginates
Antacids
H2-receptor antagonists
Proton pump inhibitors

GORD references

American Society for Gastrointestinal Endoscopy. The role of endoscopy in dyspepsia. Gastrointest Endosc. 2001;54:815-17.

Anderson LA, Murray LJ, Murphy SJ, et al. Mortality in Barrett's oesophagus: results from a population based study. Gut. 2003;52:1081-4.

Arguedas MR and Eloubeidi MA. Barrett's oesophagus: a review of costs of the illness. Pharmacoeconomics. 2001;19:1003-11.

Astarita C, Gargano D, Cutajar M, et al. Gastroesophageal reflux disease and asthma: an intriguing dilemma. Allergy. 2000;55 Suppl 61:52-55.

Avidan B, Sonnenberg A, Schnell TG, et al. Temporal associations between coughing or wheezing and acid reflux in asthmatics. Gut. 2001;49:767-72.

Bartlett DW, Evans DF, Anggiansah A, et al. A study of the association between gastro-oesophageal reflux and palatal dental erosion. Br Dent J. 1996;181:125-31.

Bolling-Sternevald E, Lauritsen K, Aalykke C, et al. Effect of profound acid suppression in functional dyspepsia: a double-blind, randomized, placebo-controlled trial. Scand J Gastroenterol. 2002;37:1395-402.

Buts JP, Barudi C, and Otte JB. Double-blind controlled study on the efficacy of sodium alginate (Gaviscon) in reducing gastroesophageal reflux assessed by 24 h continuous pH monitoring in infants and children. Eur J Pediatr. 1987;146:156-8.

Bytzer P. On-demand therapy for gastro-oesophageal reflux disease. Eur J Gastroenterol Hepatol. 2001;13 Suppl 1:19-22.

Cadiot G, Bruhat A, Rigaud D, et al. Multivariate analysis of pathophysiological factors in reflux oesophagitis. Gut. 1997;40:167-74.

Cameron AJ and Arora AS. Barrett's esophagus and reflux esophagitis: is there a missing link? Am J Gastroenterol. 2002;97:273-8.

Chatfield S. A comparison of the efficacy of the alginate preparation, Gaviscon Advance, with placebo in the treatment of gastro-oesophageal reflux disease. Curr Med Res Opin. 1999;15:152-9.

Chevalier JM, Brossard E, and Monnier P. Globus sensation and gastroesophageal reflux. Eur Arch Otorhinolaryngol. 2003;260:273-6.

Chevrel B. A comparative crossover study on the treatment of heartburn and epigastric pain: Liquid Gaviscon and a magnesium-aluminium antacid gel. J Int Med Res. 1980;8 :300-2.

Chiba N, De Gara CJ, Wilkinson JM, et al. Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease: a meta-analysis. Gastroenterology. 1997;112:1798-810.

Contencin P and Narcy P. Gastropharyngeal reflux in infants and children. A pharyngeal pH monitoring study. Arch Otolaryngol Head Neck Surg. 1992;118:1028-30.

Coughlan JL, Gibson PG, and Henry RL. Medical treatment for reflux oesophagitis does not consistently improve asthma control: a systematic review. Thorax. 2001;56:198-204.

Crozier A. The management of dyspepsia. Nurs Times. 2003;99:30-33.Delahunty JE and Ardran GM. Globus hystericus--a manifestation of reflux oesophagitis? J Laryngol Otol. 1970;84:1049-54.

Delaney BC, Moayyedi P, Forman D. Initial management strategies for dyspepsia. Cochrane Database Syst Rev. 2003;CD001961.

Dent J. Long-term aims of treatment of reflux disease, and the role of non-drug measures. Digestion. 1992;51 Suppl 1:30-4.

Dent J, Jones R, Kahrilas P, et al. Management of gastro-oesophageal reflux disease in general practice. BMJ. 2001;322:344-7.

DeVault KR. Should GERD therapy be stepped up, stepped down, or not stepped at all? Medscape Gastroenterology. 2003;5:1-4.

Deveney CW, Benner K, and Cohen J. Gastroesophageal reflux and laryngeal disease. Arch Surg. 1993;128:1021-5.

Eisen GM, Dominitz JA, Faigel DO, Goldstein JA, Kalloo AN, Petersen BT, Raddawi HM, Ryan ME, Vargo JJ, III, Young HS, Fanelli RD, Hyman NH, Wheeler-Harbaugh J. The role of endoscopy in dyspepsia. Gastrointest Endosc. 2001;54:815-817.

Farup PG. Functional dyspepsia and gastric acid: any relation? Scand J Gastroenterol. 2002;37:1349-50.

Fass R and Ofman JJ. Gastroesophageal reflux disease--should we adopt a new conceptual framework? Am J Gastroenterol. 2002;97:1901-9.

Fennerty MB. Step-up, step-down, step-in? Are we dancing or treating gerd? Evidence Based Gastroenterology. 2002;3:36-37.

Field SK. Gastroesophageal reflux and asthma: can the paradox be explained? Can Respir J. 2000;7:167-76.

Fletcher J, Wirz A, Young J, et al. Unbuffered highly acidic gastric juice exists at the gastroesophageal junction after a meal. Gastroenterology. 2001;121:775-83.

Fraser AG. Review article: gastro-oesophageal reflux and laryngeal symptoms. Aliment Pharmacol Ther. 1994;8:265-72.

Freedman J, Lindqvist M, Hellstrom PM, et al. Presence of bile in the oesophagus is associated with less effective oesophageal motility. Digestion. 2002;66:42-8.

Freeland AP, Adran GM, and Emrys-Roberts E. Globus hystericus and reflux oesophagitis. J Laryngol Otol. 1974;88:1025-31.

Galli J, Cammarota G, Calo L, et al. The role of acid and alkaline reflux in laryngeal squamous cell carcinoma. Laryngoscope. 2002;112:1861-5.

Galmiche JP, Letessier E, and Scarpignato C. Treatment of gastro-oesophageal reflux disease in adults. BMJ. 1998;316:1720-3.

Gerson LB, Shetler K, and Triadafilopoulos G. Prevalence of Barrett's esophagus in asymptomatic individuals. Gastroenterology. 2002;123:461-7.

Giacchi RJ, Sullivan D, and Rothstein SG. Compliance with anti-reflux therapy in patients with otolaryngologic manifestations of gastroesophageal reflux disease. Laryngoscope. 2000;110:19-22.

Gibson PG, Henry RL, Coughlan JL. Gastro-oesophageal reflux treatment for asthma in adults and children. Cochrane Database Syst Rev. 2003;CD001496.

Gilger MA. Pediatric otolaryngologic manifestations of gastroesophageal reflux disease. Curr Gastroenterol Rep. 2003;5:247-52.

Gonzalez ER, Bahal N, and Johnson LF. Gastroesophageal reflux and respiratory symptoms: is there an association? Proposed mechanisms and treatment. DICP. 1990;24:1064-1069.

Graham DY and Patterson DJ. Double-blind comparison of liquid antacid and placebo in the treatment of symptomatic reflux esophagitis. Dig Dis Sci. 1983;28:559-63.

Graham DY and Yamaoka Y. H. pylori and cagA: relationships with gastric cancer, duodenal ulcer, and reflux esophagitis and its complications. Helicobacter. 1998;3:145-51.

Greally P, Hampton FJ, MacFadyen UM, et al. Gaviscon and Carobel compared with cisapride in gastro-oesophageal reflux. Arch Dis Child. 1992;67:618-621.

Greason KL, Miller DL, Deschamps C, et al. Effects of antireflux procedures on respiratory symptoms. Ann Thorac Surg. 2002;73:381-5.

Green C and Mee A. GORD; Treatment and maintenance options. Prescriber. 2002;21-34.

Haag S and Holtmann G. Reflux disease and Barrett's esophagus. Endoscopy. 2003;35:112-117.

Hamdan AL, Sharara AI, Younes A, et al. Effect of aggressive therapy on laryngeal symptoms and voice characteristics in patients with gastroesophageal reflux. Acta Otolaryngol. 2001;121:868-72.

Haque M, Wyeth JW, Stace NH, et al. Prevalence, severity and associated features of gastro-oesophageal reflux and dyspepsia: a population-based study. N Z Med J. 2000;113:178-181.

Harding SM, Guzzo MR, and Richter JE. 24-h esophageal pH testing in asthmatics: respiratory symptom correlation with esophageal acid events. Chest. 1999;115:654-9.

Hatlebakk JG, Katz PO, Kuo B, et al. Nocturnal gastric acidity and acid breakthrough on different regimens of omeprazole 40 mg daily. Aliment Pharmacol Ther. 1998;12:1235-40.

Haug TT, Mykletun A, and Dahl AA. Are anxiety and depression related to gastrointestinal symptoms in the general population? Scand J Gastroenterol. 2002;37:294-8.

Higgs RH, Smyth RD, and Castell DO. Gastric alkalinization. Effect on lower-esophageal-sphincter pressure and serum gastrin. N Engl J Med. 1974;291:486-90.

Hollenz M, Stolte M, and Labenz J. [Prevalence of gastro-oesophageal reflux disease in general practice]. Dtsch Med Wochenschr. 2002;127:1007-12.

Hu FZ, Preston RA, Post JC, et al . Mapping of a gene for severe pediatric gastroesophageal reflux to chromosome 13q14. JAMA. 2000;284:325-34.

Huang RC, Forbes DA, and Davies MW. Feed thickener for newborn infants with gastro-oesophageal reflux. Cochrane Database Syst Rev. 2002;CD003211-

Hutt HJ, Tauber O, and Flach D. [Gaviscon in reflux symptoms. Results of a drug monitoring study]. Fortschr Med. 1990;108:598-600.

Ing AJ, Ngu MC, and Breslin AB. Chronic persistent cough and gastro-oesophageal reflux. Thorax. 1991;46:479-83.

Ing AJ, Ngu MC, and Breslin AB. Chronic persistent cough and clearance of esophageal acid. Chest. 1992;102:1668-71.

Irwin RS, Boulet LP, Cloutier MM, et al. Managing cough as a defense mechanism and as a symptom. A consensus panel report of the American College of Chest Physicians. Chest. 1998;114:133S-181S.

Irwin RS and Madison JM. Diagnosis and treatment of chronic cough due to gastro-esophageal reflux disease and postnasal drip syndrome. Pulm Pharmacol Ther. 2002;15:261-6.

Issing WJ, Karkos PD. Atypical manifestations of gastro-oesophageal reflux. J R Soc Med. 2003;96:477-480.

Jankowski J, Jones R, Delaney B, et al. 10-minute consultation: Gastro-oesophageal reflux disease. BMJ. 2002;325:945.

Jansen JB and Van Oene JC. Standard-dose lansoprazole is more effective than high-dose ranitidine in achieving endoscopic healing and symptom relief in patients with moderately severe reflux oesophagitis. The Dutch Lansoprazole Study Group. Aliment Pharmacol Ther. 1999;13:1611-20.

Jaspersen D, Kulig M, Labenz J, et al. Prevalence of extra-oesophageal manifestations in gastro-oesophageal reflux disease: an analysis based on the ProGERD Study. Aliment Pharmacol Ther. 2003;17:1515-20.

Joelsson B and Johnsson F. Heartburn--the acid test. Gut. 1989;30:1523-5.

Johansson KE, Boeryd B, Johansson K, et al. Double-blind crossover study of ranitidine and placebo in gastro-oesophageal reflux disease. Scand J Gastroenterol. 1986;21:769-778.

Johnson DA, Winters C, Spurling TJ, et al. Esophageal acid sensitivity in Barrett's esophagus. J Clin Gastroenterol. 1987;9:23-7.

Jones R. Gastro-oesophageal reflux disease in general practice. Scand J Gastroenterol Suppl. 1995;211:35-8.

Jones RH, Lydeard SE, Hobbs FD, et al. Dyspepsia in England and Scotland. Gut. 1990;31:401-405.

Katz PO, Hatlebakk JG, and Castell DO. Gastric acidity and acid breakthrough with twice-daily omeprazole or lansoprazole. Aliment Pharmacol Ther. 2000;14:709-14.

Katz PO. Review article: the role of non-acid reflux in gastro-oesophageal reflux disease. Aliment Pharmacol Ther . 2000;14:1539-51.

Katz PO. Gastroesophageal reflux disease--state of the art. Rev Gastroenterol Disord. 2001;1:128-38.

Kiljander TO, Salomaa ER, Hietanen EK, et al. Gastroesophageal reflux in asthmatics: A double-blind, placebo-controlled crossover study with omeprazole. Chest. 1999;116:1257-64.

Kiljander TO, Salomaa ER, Hietanen EK, et al. Chronic cough and gastro-oesophageal reflux: a double-blind placebo-controlled study with omeprazole. Eur Respir J. 2000;16:633-8.

Kinnear M, Ghosh S, and Hudson S. Gastro-oesophageal reflux disease. Pharm J. 1999;263:241-250.

Kinoshita Y, Adachi K, and Fujishiro H. Therapeutic approaches to reflux disease, focusing on acid secretion. J Gastroenterol. 2003;38 Suppl 15:13-9.

Kitchin LI and Castell DO. Rationale and efficacy of conservative therapy for gastroesophageal reflux disease. Arch Intern Med. 1991;151:448-54.

Klaus A, Swain JM, and Hinder RA. Laparoscopic antireflux surgery for supraesophageal complications of gastroesophageal reflux disease. Am J Med. 2001;111 Suppl 8A:202S-206S.

Klauser AG, Schindlbeck NE, and Muller-Lissner SA. Symptoms in gastro-oesophageal reflux disease. Lancet. 1990;335:205-208.

Klinkenberg-Knol EC, Festen HP, and Meuwissen SG. Pharmacological management of gastro-oesophageal reflux disease. Drugs. 1995;49:695-710.

Klinkenberg-Knol EC, Nelis F, Dent J, et al. Long-term omeprazole treatment in resistant gastroesophageal reflux disease: efficacy, safety, and influence on gastric mucosa. Gastroenterology. 2000;118:661-9.

Koop H. Gastroesophageal reflux disease and Barrett's esophagus. Endoscopy. 2002;34:97-103.

Koufman JA. The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury. Laryngoscope. 1991;101:1-78.

Kuipers EJ, Lundell L, Klinkenberg-Knol EC, et al. Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication. N Engl J Med. 1996;334:1018-22.

Landreneau RJ, Wiechmann RJ, Hazelrigg SR, et al. Success of laparoscopic fundoplication for gastroesophageal reflux disease. Ann Thorac Surg. 1998;66:1886-93.

Lawson M. Gastro-oesophageal reflux in infants: an evidence-based approach. Br J Community Nurs. 2003;8:296-301.

Lidums I, Lehmann A, Checklin H, et al. Control of transient lower esophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in normal subjects. Gastroenterology. 2000;118:7-13.

Lieberman D. Treatment approaches to reflux oesophagitis. Drugs. 1990;39:674-80.

Lindow SW, Regnell P, Sykes J, et al. An open-label, multicentre study to assess the safety and efficacy of a novel reflux suppressant (Gaviscon Advance) in the treatment of heartburn during pregnancy. Int J Clin Pract. 2003;57:175-9.

Logan R and Delaney B. ABC of the upper gastrointestinal tract: implications of dyspepsia for the NHS. BMJ. 2001;323:675-7.

Lovat L. Talking to patients about gastrooesophageal reflux. Prescriber. 2003;53-55.

Malmud LS, Charkes ND, Littlefield J, et al. The mode of action alginic acid compound in the reduction of gastroesophageal reflux. J Nucl Med. 1979;20:1023-8.

Mandel KG, Daggy BP, Brodie DA, et al. Review article: alginate-raft formulations in the treatment of heartburn and acid reflux. Aliment Pharmacol Ther. 2000;14:669-90.

Mansfield LE. Gastroesophageal reflux and respiratory disorders. Compr Ther. 1992;18:6-10.

Marshall BJ and Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet. 1984;1:1311-5.

McHardy G. A multicentric, randomized clinical trial of Gaviscon in reflux esophagitis. South Med J. 1978;71 Suppl 1:16-21.

McNamara D and O'Morain C. Gastro-oesophageal reflux disease and Helicobacter pylori: an intricate relation. Gut . 1999;45 Suppl 1:13-7.

Meier JH, McNally PR, Punja M, et al. Does omeprazole (Prilosec) improve respiratory function in asthmatics with gastroesophageal reflux? A double-blind, placebo-controlled crossover study. Dig Dis Sci. 1994;39:2127-33.

Miller S. Comparison of the efficacy and safety of a new aluminium-free paediatric alginate preparation and placebo in infants with recurrent gastro-oesophageal reflux. Curr Med Res Opin. 1999;15:160-8.

Mittal RK. Current concepts of the antireflux barrier. Gastroenterol Clin North Am. 1990;19:501-16.

Mohammed I, Cherkas LF, Riley SA, Spector TD, Trudgill NJ. Genetic influences in gastro-oesophageal reflux disease: a twin study. Gut. 2003;52:1085-1089.

Mokhlesi B, Morris AL, Huang CF, et al. Increased prevalence of gastroesophageal reflux symptoms in patients with COPD. Chest. 2001;119:1043-1048.

Moloy PJ and Charter R. The globus symptom. Incidence, therapeutic response, and age and sex relationships. Arch Otolaryngol. 1982;108:740-4.

Morice AH. Epidemiology of cough. Pulm Pharmacol Ther. 2002;15:253-9.

Moayyedi P, Soo S, Deeks J, Delaney B, Innes M, Forman D. Pharmacological interventions for non-ulcer dyspepsia. Cochrane Database Syst Rev. 2003;CD001960.

Mujica VR and Rao SS. Recognizing atypical manifestations of GERD. Asthma, chest pain, and otolaryngologic disorders may be due to reflux. Postgrad Med. 1999;105:53-5.

Nandurkar S and Talley NJ. Epidemiology and natural history of reflux disease. Baillieres Best Pract Res Clin Gastroenterol. 2000;14:743-57.

Nathoo V. Managing gastro-oesophageal reflux disease in primary care. Int J Clin Pract. 2001;55:465-9.

Nebel OT, Fornes MF, and Castell DO. Symptomatic gastroesophageal reflux: incidence and precipitating factors. Am J Dig Dis. 1976;21:953-6.

Nehra D, Howell P, Williams CP, et al. Toxic bile acids in gastro-oesophageal reflux disease: influence of gastric acidity. Gut. 1999;44:598-602.

Nguyen NQ and Holloway RH. Gastroesophageal reflux disease. Curr Opin Gastroenterol. 2003;19:373-378.

NICE Technology Appraisal. Guidance on the use of proton pump inhibitors (PPIs) in the treatment of dyspepsia. NICE Technology Appraisal. 2000;

Niedzielska G, Glijer E, Toman D, et al. Voice disorders in children with gastroesophageal reflux disease. Ann Univ Mariae Curie Sklodowska [Med]. 2000;55:91-4.

Nilsson M, Johnsen R, Ye W, et al. Obesity and estrogen as risk factors for gastroesophageal reflux symptoms. JAMA. 2003;290:66-72.

Noordzij JP, Khidr A, Evans BA, et al. Evaluation of omeprazole in the treatment of reflux laryngitis: a prospective, placebo-controlled, randomized, double-blind study. Laryngoscope. 2001;111:2147-51.

Novitsky YW, Zawacki JK, Irwin RS, et al. Chronic cough due to gastroesophageal reflux disease: efficacy of antireflux surgery. Surg Endosc. 2002;16:567-71.

Numans ME and de Wit NJ. Reflux symptoms in general practice: diagnostic evaluation of the Carlsson-Dent gastro-oesophageal reflux disease questionnaire. Aliment Pharmacol Ther. 2003;17:1049-55.

Nzeako UC and Murray JA. An evaluation of the clinical implications of acid breakthrough in patients on proton pump inhibitor therapy. Aliment Pharmacol Ther. 2002;16:1309-16.

O'Connor HJ and Cunnane K. Helicobacter pylori and gastro-oesophageal reflux disease--a prospective study. Ir J Med Sci. 1994;163:369-73.

Oelschlager BK, Eubanks TR, Maronian N, et al. Laryngoscopy and pharyngeal pH are complementary in the diagnosis of gastroesophageal-laryngeal reflux. J Gastrointest Surg. 2002;6:189-94.

Ofman JJ, Maclean CH, Straus WL, Morton SC, Berger ML, Roth EA, Shekelle PG. Meta-analysis of dyspepsia and nonsteroidal antiinflammatory drugs. Arthritis Rheum. 2003;49:508-518.

Ofman JJ, Shaw M, Sadik K, et al . Identifying patients with gastroesophageal reflux disease: validation of a practical screening tool. Dig Dis Sci. 2002;47:1863-9.

Omari TI, Barnett CP, Benninga MA, et al. Mechanisms of gastro-oesophageal reflux in preterm and term infants with reflux disease. Gut. 2002;51:475-9.

Page M and Jeffery H. The role of gastro-oesophageal reflux in the aetiology of SIDS. Early Hum Dev. 2000;59:127-49.

Palombini BC, Villanova CA, Araujo E, et al. A pathogenic triad in chronic cough: asthma, postnasal drip syndrome, and gastroesophageal reflux disease. Chest. 1999;116:279-84.

Paterson WG. Extraesophageal manifestations of reflux disease: myths and reality. Chest Surg Clin N Am. 2001;11:523-38.

Peghini PL, Katz PO, Bracy NA, et al. Nocturnal recovery of gastric acid secretion with twice-daily dosing of proton pump inhibitors. Am J Gastroenterol. 1998;93:763-7.

Phipps CD, Wood WE, Gibson WS, et al. Gastroesophageal reflux contributing to chronic sinus disease in children: a prospective analysis. Arch Otolaryngol Head Neck Surg. 2000;126:831-6.

Piche T, des Varannes SB, Sacher-Huvelin S, et al. Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease. Gastroenterology. 2003;124:894-902.

Poynard T. Relapse rate of patients after healing of oesophagitis--a prospective study of alginate as self-care treatment for 6 months. French Co-operative Study Group. Aliment Pharmacol Ther. 1993;7:385-392.

Poynard T, Vernisse B, and Agostini H. Randomized, multicentre comparison of sodium alginate and cisapride in the symptomatic treatment of uncomplicated gastro-oesophageal reflux. Aliment Pharmacol Ther. 1998;12:159-65.

Quigley EM. Non-erosive reflux disease: part of the spectrum of gastro-oesophageal reflux disease, a component of functional dyspepsia, or both? Eur J Gastroenterol Hepatol. 2001; 13 Suppl 1:13-8.

Raghunath A, Hungin AP, Wooff D, et al. Prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease: systematic review. BMJ. 2003;326:737-

Richter JE. Gastroesophageal reflux: diagnosis and management. Hosp Pract (Off Ed). 1992;27:59-66.

Robinson M. Drugs, bugs, and esophageal pH profiles. Yale J Biol Med. 1999;72:169-72.

Sachs G. Improving on PPI-based therapy of GORD. Eur J Gastroenterol Hepatol. 2001;13 Suppl 1:35-41.

Schindlbeck NE, Ippisch H, Klauser AG, et al. Which pH threshold is best in esophageal pH monitoring? Am J Gastroenterol. 1991;86:1138-1141.

Shaheen N and Ransohoff DF. Gastroesophageal reflux, barrett esophagus, and esophageal cancer: scientific review. JAMA. 2002;287:1972-81.

Shaker R, Castell DO, Schoenfeld PS, Spechler SJ. Nighttime heartburn is an under-appreciated clinical problem that impacts sleep and daytime function: the results of a Gallup survey conducted on behalf of the American Gastroenterological Association. Am J Gastroenterol. 2003;98:1487-1493.

Shin JM and Sachs G. Restoration of acid secretion following treatment with proton pump inhibitors. Gastroenterology. 2002;123:1588-97.

Smit CF, van Leeuwen JA, Mathus-Vliegen LM, et al. Gastropharyngeal and gastroesophageal reflux in globus and hoarseness. Arch Otolaryngol Head Neck Surg. 2000;126:827-30.

Sontag SJ, O'Connell S, Khandelwal S, et al. Most asthmatics have gastroesophageal reflux with or without bronchodilator therapy. Gastroenterology. 1990;99:613-620.

Spechler SJ. Epidemiology and natural history of gastro-oesophageal reflux disease. Digestion. 1992;51 Suppl 1:24-9.

Talley NJ. Review article: dyspepsia: how to manage and how to treat? Aliment Pharmacol Ther. 2002; 16 Suppl 4:95-104.

Talley NJ. Dyspepsia: management guidelines for the millennium. Gut. 2002;50 Suppl 4:iv72-iv78.

Taminiau JA. Gastro-oesophageal reflux in children. Scand J Gastroenterol Suppl. 1997;223:18-20.

Tasker A, Dettmar PW, Panetti M, et al. Reflux of gastric juice and glue ear in children. Lancet. 2002;359:493-

Tauber S, Gross M, and Issing WJ. Association of laryngopharyngeal symptoms with gastroesophageal reflux disease. Laryngoscope. 2002;112:879-86.

Todd JA, Johnston DA, and Dillon JF. The changing spectrum of gastroesophageal reflux disease. Eur J Cancer Prev . 2002;11:215-9.

Treem WR, Davis PM, and Hyams JS. Gastroesophageal reflux in the older child: presentation, response to treatment and long-term follow-up. Clin Pediatr (Phila). 1991;30 :435-40.

Tucci F, Resti M, Fontana R, et al. Gastroesophageal reflux and bronchial asthma: prevalence and effect of cisapride therapy. J Pediatr Gastroenterol Nutr. 1993;17:265-70.

Tytgat GN. Review article: treatment of mild and severe cases of GERD. Aliment Pharmacol Ther. 2002;16 Suppl 4:73-8.

Tytgat GN. Review article: management of mild and severe gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2003;17 Suppl 2:52-6.

Uzan M, Uzan S, Sureau C, et al. [Heartburn and regurgitation in pregnancy. Efficacy and innocuousness of treatment with Gaviscon suspension]. Rev Fr Gynecol Obstet. 1988;83:569-72.

Vaezi MF and Richter JE. Importance of duodeno-gastro-esophageal reflux in the medical outpatient practice. Hepatogastroenterology. 1999;46:40-7.

Vakil N. Review article: cost-effectiveness of different GERD management strategies. Aliment Pharmacol Ther. 2002;16 Suppl 4:79-82.

Valori RM, Brown CM, Strangeways P, et al. Reducing community dyspepsia drug costs: a controlled trial. Gut. 2001;49:495-501.

Vandenplas Y, Belli D, Benhamou P, et al. A critical appraisal of current management practices for infant regurgitation--recommendations of a working party. Eur J Pediatr. 1997;156:343-57.

Vandenplas Y and Hassall E. Mechanisms of gastroesophageal reflux and gastroesophageal reflux disease. J Pediatr Gastroenterol Nutr. 2002;35:119-36.

van Pinxteren B, Numans ME, Bonis PA, Lau J. Short-term treatment with proton pump inhibitors, H2-receptor antagonists and prokinetics for gastro-oesophageal reflux disease-like symptoms and endoscopy negative reflux disease. Cochrane Database Syst Rev. 2001;CD002095.

van Pinxteren B, Numans ME, Lau J, de Wit NJ, Hungin AP, Bonis PA. Short-term treatment of gastroesophageal reflux disease. J Gen Intern Med. 2003;18:755-763.

Vantrappen G, Tack J, Huyberechts G, et al. Studies on the relationship between esophageal acid exposure, mucosal lesions and heartburn using an acid exposure sensor. Scand J Gastroenterol. 2002;37:1253-8.

Waldum HL and Brenna E. Personal review: is profound acid inhibition safe? Aliment Pharmacol Ther. 2000;14:15-22.

Ward AE. Comparative study of Algicon versus Gaviscon in symptomatic gastro-oesophageal reflux. Br J Clin Pract Suppl. 1989;66:52-5.

Waring JP, Feiler MJ, Hunter JG, et al. Childhood gastroesophageal reflux symptoms in adult patients. J Pediatr Gastroenterol Nutr. 2002;35:334-8.

Washington N. Gastric distribution and residence time of two anti-reflux formulations. Int J Pharm. 1987;39:163-171.

Washington N. Investigation into the barrier action of an alginate gastric reflux suppressant, Liquid Gaviscon. Drug Invest. 1987;2:23-30.

Washington N, Greaves JL, and Wilson CG. Effect of time of dosing relative to a meal on the raft formation of an anti-reflux agent. J Pharm Pharmacol. 1990;42:50-53.

Washington N. Investigation into the barrier action of an alginate gastric reflux suppressant, Liquid Gaviscon. Drug Invest. 1990;2:23-30.

Washington N, Greaves JL, and Iftikhar SY. A comparison of gastro-oesophageal reflux in volunteers assessed by ambulatory pH and gamma monitoring after treatment with either Liquid Gaviscon or Algicon Suspension. Aliment Pharmacol Ther. 1992;6:579-588.

Washington N, Wilson CG, Williams DL, et al. An investigation into the effect of cimetidine pre-treatment on raft formation of an anti-reflux agent. Aliment Pharmacol Ther. 1993;7:553-559.

Washington N, Sykes J, Parker MA, et al. Time to onset of action of sodium alginate, ranitidine, omeprazole and water based on oesophageal pH. Gastroenterology. 1999;116:4 (Abstract).

Welage LS and Berardi RR. Evaluation of omeprazole, lansoprazole, pantoprazole, and rabeprazole in the treatment of acid-related diseases. J Am Pharm Assoc (Wash). 2000;40:52-62.

Weldon AP and Robinson MJ. Trial of gaviscon in the treatment of gastro-oesophageal reflux of infancy. Aust Paediatr J. 1972;8:279-281.

Williams DL, Haigh GG, and Redfern JN. The symptomatic treatment of heartburn and dyspepsia with Liquid Gaviscon: a multicentre general practitioner study. J Int Med Res. 1979;7:551-5.

Wilson CG, May HA, and Hardy JG. Gastric emptying of antacids. J Pharm Pharmacol. 1983;35:38-

Wong RK, Hanson DG, Waring PJ, et al. ENT manifestations of gastroesophageal reflux. Am J Gastroenterol. 2000;95:15-22.

Wurm P and De Caestecker J. Managing reflux oesophagitis. Practitioner. 2002;246:559, 562, 564 passim.

Zalesska-Krecicka M, Krecicki T, Iwanczak B, et al. Laryngeal manifestations of gastroesophageal reflux disease in children. Acta Otolaryngol. 2002;122:306-10.

Zaloga GP, Chernow B, Chin R, et al. Gastroesophageal fundoplication improves symptoms in refractory asthma. Am Surg. 1983;49:403-4.

LPR / EOR references

Astarita C, Gargano D, Cutajar M, et al. Gastroesophageal reflux disease and asthma: an intriguing dilemma. Allergy. 2000;55 Suppl 61:52-55.

Avidan B, Sonnenberg A, Schnell TG, et al. Temporal associations between coughing or wheezing and acid reflux in asthmatics. Gut. 2001;49:767-72.

Belafsky PC, Postma GN, Amin MR, et al. Symptoms and findings of laryngopharyngeal reflux. Ear Nose Throat J. 2002;81:10-3.

Benini L, Ferrari M, Sembenini C, et al. Cough threshold in reflux oesophagitis: influence of acid and of laryngeal and oesophageal damage. Gut. 2000;46:762-7.

Book DT, Rhee JS, Toohill RJ, et al. Perspectives in laryngopharyngeal reflux: an international survey. Laryngoscope. 2002;112:1399-406.

Chevalier JM, Brossard E, and Monnier P. Globus sensation and gastroesophageal reflux. Eur Arch Otorhinolaryngol. 2003;260:273-6.

Coughlan JL, Gibson PG, and Henry RL. Medical treatment for reflux oesophagitis does not consistently improve asthma control: a systematic review. Thorax. 2001;56:198-204.

Delahunty JE and Ardran GM. Globus hystericus--a manifestation of reflux oesophagitis? J Laryngol Otol. 1970;84:1049-54.

Deveney CW, Benner K, and Cohen J. Gastroesophageal reflux and laryngeal disease. Arch Surg. 1993;128:1021-5.

Eubanks TR, Omelanczuk P, Hillel A, et al. Pharyngeal pH measurements in patients with respiratory symptoms before and during proton pump inhibitor therapy. Am J Surg. 2001;181:466-70.