Heartburn in Pregnancy

Heartburn due to reflux of gastric contents into the oesophagus is particularly prevalent during pregnancy. GORD and heartburn are reported in 45-85% of women during pregnancy,[Boussard, 1998] and up to 25% of pregnant women suffer daily symptoms of heartburn.[Nebel, 1976]

Pregnancy is associated with decreased Lower Oesophageal Sphincter (LOS) pressure, more frequent episodes of reflux and upright reflux. [Al-Amri SM, 2002] Symptoms are rarely severe, however, and subside post partum, as soon as the woman's weight returns to normal . The symptoms can, however, cause greater distress than other potentially more serious conditions, interfering with sleep and diet, and can indirectly affect the health of the unborn child. Although endoscopic and other diagnostic tests are not usually needed, they must be used with caution in pregnant women due to potential foetal risks.

Owing to heartburn in pregnancy potentially interfering with sleep and diet, and its potential affect on the health of the unborn child, a safe and effective treatment is important in this specific patient population.

Causes of GORD in pregnancy

  • Weight gain associated with pregnancy can increase the symptoms of GORD, the enlarging uterus resulting in increased intra-abdominal pressure.
  • Increased serum concentrations of oestrogen and progesterone can lead to LOS dysfunction by their effects as muscle relaxants.

GORD in pregnancy should be managed with a step up algorithm. Click here to find out more...>>

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